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Question: From New Jersey, USA: I was just wondering if it is possible to localize a virus only in the pancreas and keep it there. If I were to put a virus with beta cell DNA in the lytic cycle, can it maintain itself only in the pancreas? Here's what I'm thinking: Get a virus. Kill it’s DNA, put the protein coat in with the beta cells. The virus takes the beta cell DNA, which is injected into the pancreas, if possible, one time, if not, through a monthly injection into the arm or stomach. It attacks T cells, so add immunosuppressant drugs first, then the virus injects DNA into localized T cells. The T cells in the pancreas become beta cells, which produce islet cells. The islet cells produce insulin and the virus continues to attacks T cells to become beta cells due to the lytic cycle. One becomes insulin independent, but the virus must stay localized in pancreas; it must not leave the pancreas. The problem is that I don't know how to get the virus directly to the pancreas. It would be CD4+ T cells are what causes adaptive immune responses, so the virus would have to react to the T cell. Answer: It's a nifty idea, but there is no way to actually do what you are proposing. Maybe some clever research virologist or immunologist will figure out a way to do it though. SB DTQ-20070819024434 Original posting 28 Aug 2007 Posted to Research: Cure

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Guide to CWD Help with Error Messages Index Privacy Policy Search Site Map --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Get CWD Products Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Tue Aug 28 18:53:10 2007
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